Can oral hyaluronic acid be used to treat inflammation, protect skin and fight aging? Professor reveals a question

Associate Professor Lin Zonghua from the Department of Cosmetics Application at Huaxia University of Technology contacted me by email on 2022-5-11. He said:

[There are still many incorrect information and products on the Taiwan market. The Consumers Cultural and Educational Foundation of the Republic of China (simplified Chinese Consumer Foundation) is a non-profit social group legal entity. I serve as the Committee of the Inspection Committee of the Consumer Foundation for Services without any responsibilities, and assist the Consumer Foundation in the inspection and publicity of consumer products. …… Read Professor Lin’s series of articles on the Internet [Scientific Nursing and Health Care ~ Avoid Communication and Prevent Misconduct] have high reference value. I wonder if Professor Lin agrees that he authorized to quote your article in the article he helped the Vaccine Foundation write "Beauty Drink"? To avoid misinformation and misinformation, protect the rights of more Taiwanese consumers. Finally, thank you for reading this letter and look forward to your articles on the Internet [Scientific Nursing and Health Care ~ Avoiding rumor and preventing misguided] to benefit more consumers. 】

Three days later, Associate Professor Lin Zonghua sent another email:

Professor Lin: Currently, there are many oral hyaluronic acid (Hyaluronan, Hyaluronic acid) health products on the Taiwan market. The main effects are correct to protect knee joints, skin moisturizing and anti-aging, and eye care. In response to the situation in Taiwan's hyaluronic acid health care products market, the Aiding the CDC is preparing to write about oral hyaluronic acid health care products. I wonder if I can ask Professor Lin for some opinions on oral hyaluronic acid health care products?

In fact, readers have long asked me if oral hyaluronic acid is really effective, for example, Gary was the most effective gelatin on 2021-3-24? Messages in the response column of this article. So, today I'll give a total reply here.

Hyaluronic acid and gelatin are both huge molecules (the former is glycogenic and the latter is protein), and it is impossible to penetrate the kidney wall and enter the blood circulation. Therefore, in regular medical conditions, their applications are usually performed in the form of injections, such as subcutaneous or quasi-sectional injections. However, health care products practitioners say oral hyaluronic acid and gelatin can also achieve the same effect as injections.

Health care product operators certainly know that hyaluronic acid and gelatin cannot penetrate the kidney wall, so they did not think about creating the so-called small molecule hyaluronic acid or gelatin. But can small molecules penetrate the kidney wall?

Succrose is a double sugar that is broken down into two single sugars (glucose and fructose) in the kidneys. Only single sugars can pass through the walls of the kidney and enter the blood circulation. However, hyaluronic acid is composed of about 40,000 single sugars, and the so-called small molecule hyaluronic acid is composed of several thousand single sugars. How can it be possible to penetrate the kidney wall?

Health products practitioners of course also know that the so-called small molecule hyaluronic acid cannot pass through the kidney wall, so they paid for some researchers to publish some plausible papers and proposed a different theory of "certifying" how small molecule hyaluronic acid can enter the blood circulation, such as what passes through the cell gap, absorption by the blind kidney, etc. For those who know physiology, these strange arguments are just hard to break, but to the general public, they are like iron certificates.

You should know that all research on oral hyaluronic acid is supported by health care providers. However, researchers have not confessed such conflicts of interest in the paper, and the reason why they can avoid rules is that these papers are published in low-level journals that urgently need to be conquered.

The American College of Wettage Diseases and the American Orthopedic Medical Association both mentioned in their guidance that the use of injection of hyaluronic acid is used to treat hyaluronic acid, but it did not mention the use of oral hyaluronic acid is used to treat hyaluronic acid. The American Academy of Skin Medicine also mentioned the use of injection of hyaluronic acid to eliminate anacondas and hyaluronic acid to protect the skin, but it was not mentioned at all.

WebMD has published an article on hyaluronic acid, which says: "People usually use oral hyaluronic acid to treat urinary tract infections, gastric acid reflux, dry eyes, wounds, skin aging and many other conditions, but there is no good scientific evidence to support these uses."

Medicinenet also published an article on hyaluronic acid, which says: "Many people want to use hyaluronic acid to prevent aging. In fact, hyaluronic acid has been promoted as "Spring of Youth" &ldquo." However, there is no evidence to support this statement that oral or smear on the skin can prevent changes related to aging. "

Harvard University also published By the way, doctor: Is there any drawback to hyaluronic acid capsules? (I'll ask the doctor: Are there any drawback to hyaluronic acid capsules?). Author Donald Reilly said: "As far as we know, if taken orally, almost no hyaluronic acid can reach the knee, so it's hard to see how the capsule has a great effect. But many people have vowed to be effective, just like glucosamine. Since the only possible harm to oral hyaluronic acid is the money bag, I don't waste energy and argue that oral hyaluronic acid is not useful."

In other words, people who believe that oral hyaluronic acid are effective are spending their own money and being a doctor, so why waste time and energy to fight with them.

Unfortunately, it is because the regular medical community has to spend time and energy to correct it that it can tolerate rape, causing the hyaluronic acid myth.

Original text: Can oral hyaluronic acid treat inflammation and protect skin and fight aging?